PT-141 – 10mg

PT-141, also known as Bremelanotide, is a synthetic peptide studied for its potential to influence sexual arousal and behavior. Derived from Melanotan II, a peptide initially developed for tanning, PT-141 was later found to have effects on sexual function. Unlike traditional treatments that target blood flow, PT-141 works through the central nervous system, making it a unique approach to addressing sexual dysfunction.

As a melanocortin receptor agonist, PT-141 activates MC3-R and MC4-R receptors, which regulate various physiological functions, including sexual response. By targeting these receptors, PT-141 influences sexual desire and arousal through brain pathways, affecting the brain’s response to sexual stimuli rather than increasing blood circulation. This mechanism makes PT-141 different from phosphodiesterase type 5 (PDE5) inhibitors like sildenafil (Viagra), which primarily improve blood flow.

Researchers have explored PT-141’s potential in treating sexual dysfunction in both men and women. Studies suggest that PT-141 enhances sexual desire and arousal by acting directly on the central nervous system. Because of this, scientists see PT-141 as a possible alternative for individuals who do not respond to blood flow-based treatments. Women with hypoactive sexual desire disorder (HSDD) and men with erectile dysfunction (ED) have been among the key focus groups in research on PT-141.

Beyond sexual function, some studies suggest that PT-141 may have additional physiological effects. Researchers are exploring whether it can influence mood, energy levels, and stress responses through its action on the melanocortin system. Since PT-141 affects brain chemistry, ongoing studies aim to determine if it has broader neurological benefits.

Clinical trials have examined the safety and efficacy of PT-141 for sexual health. While results indicate promising effects on arousal and desire, researchers continue to investigate its long-term effects, optimal dosing, and potential side effects. Reported side effects include nausea, flushing, and headaches, but more research is needed to understand how to minimize these reactions.

Since its discovery, PT-141 has remained a focus in sexual health research. Scientists continue to explore its role in addressing centrally mediated sexual dysfunction and its potential applications beyond sexual health. As research advances, PT-141 may offer new treatment options for individuals seeking alternatives to traditional blood flow-targeting therapies.

For Research Use Only.