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OC Peptides

BPC Wolverine

BPC Wolverine

$120.00 USD
$120.00 USD
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BPC Wolverine is an innovative blend of three peptides: BPC-157, TB-500, and MGF. This combination is designed for researched accelerated healing and cellular rejuvenation. While BPC-157 and TB-500 are known for their research potential in tissue repair and anti-inflammatory effects, MGF (Mechano Growth Factor) plays a role in muscle repair and growth. BPC Wolverine research and scientific exploration focuses on these peptides, particularly in the context of their individual and potential synergistic effects.

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BPC Wolverine
BPC Wolverine
$120.00/ea		 $0.00
$120.00/ea $0.00

BPC Wolverine

Introduction to BPC Wolverine

BPC Wolverine is an innovative blend of three peptides: BPC-157, TB-500, and MGF. This combination is designed for accelerated healing and cellular rejuvenation. While BPC-157 and TB-500 are known for their potential in tissue repair and anti-inflammatory effects, MGF (Mechano Growth Factor) plays a role in muscle repair and growth. This page focuses on the research and scientific exploration of these peptides, particularly in the context of their individual and potential synergistic effects.


Individual Research on BPC-157, TB-500, and MGF

BPC-157: Tissue Repair and Healing

  • Wound Healing Studies: Research involving murine models with acute or chronic wounds showed that BPC-157 treatment significantly increased collagen and blood vessel formation compared to placebo, indicating its potential to enhance tissue repair.
  • Connective Tissue Recovery: Studies suggest BPC-157 may aid in the recovery of connective tissues by promoting tendon explant growth and increasing resilience to oxidative stress. It may enhance the movement and dispersion of tendon fibroblasts, potentially through the FAK-paxillin pathway.

TB-500: Cellular Motility and Wound Healing

  • Murine Wound Healing: A study conducted in 1999 reported that murine models treated with TB-500 showed a 41% increase in re-epithelialization of wounds. After seven days, wounds treated with TB-500 had contracted more significantly than those treated with saline.
  • Pressure Ulcer Clinical Trial: In a 2006 clinical trial, patients with pressure ulcers treated with TB-500 showed signs of healing, suggesting its potential in wound management.
  • Ligament Healing: Research indicates that TB-500 may improve the healing of transected medial collateral ligaments in murine models, with observed improvements in collagen formation and mechanical properties of regenerating tissues.

MGF: Muscle Repair and Growth

  • Muscle Regeneration: While specific studies on MGF in the BPC Wolverine blend are not detailed here, MGF is mainly recognized for its role in muscle repair and growth, particularly following exercise or muscle damage.

Potential Synergistic Effects of the Blend

While there are no specific studies combining BPC-157, TB-500, and MGF in a single research model, the individual properties of these peptides suggest a potential for synergistic effects in tissue repair, wound healing, and muscle regeneration. Combining these peptides could enhance overall healing processes, though more research is needed to confirm these effects.


Conclusion

BPC Wolverine, a blend of BPC-157, TB-500, and MGF, represents a promising area in peptide research, with each component bringing unique properties to the table. While individual studies on these peptides show potential in various aspects of healing and tissue regeneration, further research is necessary to understand this blend's synergistic effects fully. 

References:

  1. Seiwerth, S., Milavic, M., Vukojevic, J., Gojkovic, S., Krezic, I., Vuletic, L. B., Pavlov, K. H., Petrovic, A., Sikiric, S., Vranes, H., Prtoric, A., Zizek, H., Durasin, T., Dobric, I., Staresinic, M., Strbe, S., Knezevic, M., Sola, M., Kokot, A., Sever, M., … Sikiric, P. (2021). Stable Gastric Pentadecapeptide BPC 157 and Wound Healing. Frontiers in pharmacology, 12, 627533. https://doi.org/10.3389/fphar.2021.627533
  2. Maar, K., Hetenyi, R., Maar, S., Faskerti, G., Hanna, D., Lippai, B., Takatsy, A., & Bock-Marquette, I. (2021). Utilizing Developmentally Essential Secreted Peptides Such as Thymosin Beta-4 to Remind the Adult Organs of Their Embryonic State-New Directions in Anti-Aging Regenerative Therapies. Cells, 10(6), 1343. https://doi.org/10.3390/cells10061343
  3. National Center for Biotechnology Information. “PubChem Compound Summary for CID 132558700, CID 132558700” PubChem, https://pubchem.ncbi.nlm.nih.gov/compound/132558700
  4. National Center for Biotechnology Information. “PubChem Compound Summary for CID 9941957” PubChem, https://pubchem.ncbi.nlm.nih.gov/compound/Bpc-157
  5. Gurtner GC, Werner S, Barrandon Y, Longaker MT. Wound repair and regeneration. Nature. 2008 May 15;453(7193):314-21. doi: 10.1038/nature07039. PMID: 18480812. https://pubmed.ncbi.nlm.nih.gov/18480812/
  6. Santra, M., Zhang, Z. G., Yang, J., Santra, S., Santra, S., Chopp, M., & Morris, D. C. (2014). Thymosin β4 up-regulation of microRNA-146a promotes oligodendrocyte differentiation and suppression of the Toll-like proinflammatory pathway. The Journal of biological chemistry, 289(28), 19508–19518. https://doi.org/10.1074/jbc.M113.529966
  7. Sikiric, Predrag et al. “Brain-gut Axis and Pentadecapeptide BPC-157: Theoretical and Practical Implications.” Current neuropharmacology vol. 14,8 (2016): 857-865. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333585/#r1
  8. Chang, Chung-Hsun et al. “The promoting effect of pentadecapeptide BPC-157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.” Journal of applied physiology (Bethesda, Md. : 1985) vol. 110,3 (2011): 774-80. doi:10.1152/japplphysiol.00945.2010. https://pubmed.ncbi.nlm.nih.gov/21030672/
  9. Katherine M. Malinda et.al, Thymosin β4 Accelerates Wound Healing, Journal of Investigative Dermatology, Volume 113, Issue 3, 1999, Pages 364-368, ISSN 0022-202X, https://www.sciencedirect.com/science/article/pii/S0022202X15405950
  10. Study of Thymosin Beta 4 in Patients With Pressure Ulcers. https://www.clinicaltrials.gov/ct2/show/NCT00382174
  11. S Seiwerth, et al. “BPC-157’s effect on healing.” Journal of physiology, Paris vol. 91,3-5 (1997): 173-8. doi:10.1016/s0928-4257(97)89480-6. https://pubmed.ncbi.nlm.nih.gov/9403790/
  12. Xu B, Yang M, Li Z, Zhang Y, Jiang Z, Guan S, Jiang D. Thymosin β4 enhances the healing of medial collateral ligament injury in rat. Regul Pept. 2013 Jun 10;184:1-5. doi: 10.1016/j.regpep.2013.03.026. https://pubmed.ncbi.nlm.nih.gov/23523891/
  13. Pevec D, Novinscak T, Brcic L, Sipos K, Jukic I, Staresinic M, Mise S, Brcic I, Kolenc D, Klicek R, Banic T, Sever M, Kocijan A, Berkopic L, Radic B, Buljat G, Anic T, Zoricic I, Bojanic I, Seiwerth S, Sikiric P. Impact of pentadecapeptide BPC-157 on muscle healing impaired by systemic corticosteroid application. Med Sci Monit. 2010 Mar;16(3):BR81-88. PMID: 20190676. https://pubmed.ncbi.nlm.nih.gov/20190676/
  14. Srivastava, D., Ieda, M., Fu, J., & Qian, L. (2012). Cardiac repair with thymosin β4 and cardiac reprogramming factors. Annals of the New York Academy of Sciences, 1270, 66–72. https://doi.org/10.1111/j.1749-6632.2012.06696.x
  15. Bock-Marquette, I., Saxena, A., White, M. D., Dimaio, J. M., & Srivastava, D. (2004). Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature, 432(7016), 466–472. https://doi.org/10.1038/nature03000